Brorin
[Brain-specific chordin-like protein] The approved gene symbol is VWC2 [von Willebrand factor C domain-containing protein 2].
Brorin is a secreted protein in mice and humans identified by Koike et al (2007). Mouse Brorin is expressed in neurons of mouse embryos and adult human brain.
Mouse Brorin inhibits the activity of bone morphogenetic proteins BMP2 and BMP6 in mouse pre-osteoblastic MC3T3-E1 cells.
Brorin has been shown to promote the development of neurons, but not the development of
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