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BBC1

[breast basic conserved protein 1] This gene has been identified by Adams et al (1992) who reported that it is differentially expressed in tumors of the female breast and may encode a tumor suppressor as it is expressed in significantly higher levels in benign breast lesions than in carcinomas. Moerland et al (1997) have excluded BBC1 as a candidate breast tumor suppressor.

Sequence comparisons between human BBC1, Drosophila melanogaster BBC1 (CG4651 gene) (Helps et al, 1995) and plant BBC1 (Bertauche (1994) indicate that BBC1 is RPL13 [ribosomal protein L13], which is a component of the 60S ribosome (60S ribosomal protein L13) (Olvera and Wool, 1994).

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