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ARVD1

[Arrhythmogenic right ventricular cardiomyopathy type 1] Autosomal dominant arrhythmogenic right ventricular dysplasia/cardiomyopathy (abbr. ARVD/C) is characterized by progressive fibrofatty replacement of the myocardium that predisposes to ventricular tachycardia and sudden death in young individuals and athletes. Beffagna et al (2005) have reported that the cause of ARVD1 is a nucleotide substitution in the 5'-UTR of the gene encoding TGF-beta-3.

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