AIGGGLSSVGGGSSTIKY |
AI-hemocidin 1 |
CC16 |
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[abalone intestine GI digest peptide; abalone intestine gastrointestinal digest peptide] this peptide with the sequence PFNQGTFAS has been isolated from digests of abalone [Haliotis discus hannai (H. discus hannai)] by virtue of its ability to inhibit the passive cutaneous anaphylaxis reaction in mice. The purified peptide attenuates histamine release and the production of pro-inflammatory cytokines, such as TNF-alpha, IL1-beta, and IL6 induced in human mast cells by phorbol 12-myristate 13-acetate plus calcium ionophore A23187 . (HMC-1 cells
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