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viral dUTPases

[viral dUTPase]

These enzymes are the viral counterparts of cellular dUTPase. Ariza et al (2014) have reported that several viral dUTPases (viral deoxyuridine triphosphate nucleotidohydrolases) possess immunomodulatory activities. They act as virus-associated molecular patterns and may play a role in the pathophysiology of diseases caused by these viruses. Viral dUTPases investigated include:

HSV-6A dUTPase [HSV-6A U45 protein] (Herpesvirus-6A dUTPase [Herpesvirus-6A U45 protein])

HHV-8 dUTPase [HHV-8 orf54 protein] (human herpesvirus type 8 orf54 protein) ( ... ... ... ... ... Subscribe to continue reading! ... ...

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