viral IL1-beta receptor |
viral IL8 |
CD336 |
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(abbr. vIL6) Human herpesvirus 8 (HHV-8) or Kaposi sarcoma-associated herpesvirus (see: KSHV) is a human herpesvirus that has been identified with high frequency in all epidemiological forms of the AIDS-related Kaposi's sarcoma (for review see also: Suthaus et al, 2011). Viral IL6 is not essential for establishment, maintenance, or reactivation from latency in cell culture and is not involved in the survival of infected BJAB B-cells in low serum (Chen L and Lagunoff M, 2007).
The genome of HHV-8 (open reading frame K2; KSHV orfK2) encodes a structural homolog of IL6,
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