Vasoinhibins |
Vasopressin |
Mitocryptide-CS1 |
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abbr. VNP (a term with multiple meanings). This synthetic peptide of 27 amino acids (Wei et al, 1993) possesses the 22 amino acid structure of the cardiovascular selective peptide CNP [C-type natriuretic peptide] and the 5 amino acid carboxyterminus of ANF [Atrial natriuretic factor]. The peptide combines the venodilating actions of CNP, the natriuretic actions of ANF, and unique arterial vasodilating actions not associated with either ANF or CNP. It down-regulates CNP receptor expression in cardiomyocytes and fibroblasts (Lu et al, 2004). VNP
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