tumor-educated platelets

abbr. TEPs; also Tumor-educated blood platelets; also: cancer-educated platelets, educated platelets. These collective terms refer to platelets that are found in tumors, where the interaction with cancer cells changes their phenotype, as shown by changes in gene expression, including of genes encoding receptors, various proteins and glycoproteins, adhesion molecules, nucleic acids. These tumor-educated platelets can enter the circulation and promote tumor growth and metastasis (for overview see: Zhang et al, 2017; Best et al, 2017; In 't Veld SGJG Wurdinger T, 2019; Roweth HG and Battinelli EM, 2021; Najafi S et al, 2024) (for context compare also: educated cells).

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Entry last modified: April 2024