tryptophyllin AcT-2 |
tryptophyllin PhT-3 |
AP1 peptide |
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This peptide, EGKPYWPPPFLPE (Glu-Gly-Lys-Pro-Tyr-Trp-Pro-Pro-Pro-Phe-Leu-Pro-Glu), has been isolated from the skin secretion of the red-eye leaf frog, Agalychnis callidryas (Wang et al, 2015). The peptide is a member of a group of small (4-14 amino acids), heterogenous peptides, termed Tryptophyllins, which are found mostly in the skins of hylid frogs from the genera Phyllomedusa and Litoria. The mature peptide possesses the canonical N-terminal pGlu residue that arises from post-translational modification of a Gln residue. The synthetic peptide has been shown to antagonize the effect of Bradykinin on rat
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