tribbles
abbr. trbl. The Drosophila melanogaster gene tribbles (gene: CG5408) encodes a protein that controls the cell cycle by timing of mitosis in the prospective mesoderm (Seher et al, 2000). The fly protein also controls cell migration during embryonic development, acting as a negative regulator of the Slbo [slow border cells] gene, which encodes aq transcription factor required for migration of border cells during Drosophila oogenesis (Rorth et al, 2000).
In some tissues such as the eye (Price et al, 2002), Drosophila Schneider-2 cells (S2 cells) (Bettencourt-Dias et al, 2004), tribbles blocks
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