transitional cells |
transitional B-lymphocytes |
hK8 |
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[transitional B-cell]
[transitional B-lymphocytes] This collective term is used to describe immature B-cells, which can be distinguished from mature B-cells by variations in antigenic specificity, relative responsiveness to B-cell receptor signals, TLR receptor signaling, and other co-receptors, as well as cytokine production. Transitional B-cells constitute a heterogenous population of cells. They stand between immature B-cells as found in the bone marrow (developing from Pro-B-cells that then develop into pre-B-cells) and peripheral mature B-cells. They are those immature B-cells that have generated a functional
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