tabinhibitin 2 |
Tablysin-15 |
As60A |
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Tabinhibitin 1 and tabinhibitin 2 are two proteins from the salivary gland of the horsefly Tabanus yao (Diptera, Tabanidae) (Xu et al, 2008). They both act as potent platelet aggregation inhibitors. tabinhibitin 2 has been shown to inhibit platelet aggregation induced by agonists such as ADP, arachidonic acid, TMVA (a snake C-type lectin-like protein from Trimeresurus mucrosquamatus venom that activates platelet via GPIb), stejnulxin (a snake C-type lectin-like protein from Trimeresurus stejnegeri venom that is a potent platelet agonist acting specifically via GPVI), U46619 (a thromboxane A2 analog), and thrombin.
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