sweat gland clear cells |
Sweat gland factor |
oxidized Galectin-1 |
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[sweat gland dark cell, dark cells of the sweat gland, dark cell of the sweat gland; dark cells of sweat glands]
This cell type, identifiable by conventional microscopy (Munger, 1961), is found in the secretory coils of eccrine sweat glands together with clear cells and myoepithelial cells that are thought to provide mechanical support and form a major niche for sweat gland stem cells and progenitor cells. All three cell types are derived from the embryonic ectoderm.
Dark cells have relatively few mitochondria and membrane villi, contain cytoplasmic electron-dense granules and secrete periodic acid–Schiff (PAS)-positive diastase-resistant glycoproteins, produce the antimicrobial peptide
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