SGP28 |
SGP-beta |
Non-ELR Chemokines |
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[surface glycoprotein 60] This murine antigen has been identified by Reiser (1990). sgp-60 is expressed on virtually all lymphocytes of both T-cell and B-cell origin. The antigen participates in cell activation of CD4(+) T-cells through the T-cell receptor / CD3 complex. Engagement of sgp-60 with a specific monoclonal antibody can inhibit IL2 production, IL2 receptor expression, and T-cell proliferation.
Cabrero et al (1993) have demonstrated that sgp-60 is identical with BCM1 [B-cell activation marker 1] and that the sgp-60 antigen is the murine
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