ribosomal protein L3 |
ribosomal protein L7 |
interferon-related developmental regulator-1 |
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abbr. and approved gene symbol: RPL5. This protein is a component of the 60S subunit of ribosomes (60S ribosomal protein L5) (Kenmochi et al, 1998). The human cDNA has been cloned by Frigerio et al (1995). For gene structure see also: Yoshiyama et al (2002).
Role as moonlighting protein
Apart from its role as a structural component of the 60S ribosome subunit, ribosomal protein L5 has another function and thus can be regarded as a member of a growing group of proteins referred to as moonlighting proteins.
Dai et al (2006) have reported that ribosomal protein L5 binds to MDM2 [murine double minute 2 homolog]; called also HDM2), an E3 ubiquitin
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