ribosomal protein L13a

abbr. RPL13a. This protein is a component of the 60S subunit of ribosomes (60S ribosomal protein L13a) L13a is a ribosomal protein involved in translational control in eukaryotic cells. For gene structure see also Yoshihama et al (2002).

L13a appears to have secondary functions independent of its involvement in protein biosynthesis. Mazumder et al (2003) have reported the controlled release of L13a from ribosomes, which becomes phosphorylated and then functions to silence translation of specific genes. Mukhopadhyay et al (2008) have shown that IFN-gamma activates a kinase cascade in which DAPK1 [death-associated protein kinase-1] activates ZIPK [ZIP kinase ... ... ... ...
 
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Entry last modified: December 2014