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renal inhibitory factor

abbr. RIF (a term with multiple meanings). This biochemically uncharacterized factor reduces the ability of the liver to function as an extrarenal source of erythropoietin (Naughton et al, 1981; Dornfest et al, 1985). It acts as an inhibitor of HEF [hepatic erythropoietic factor], a factor that increases the formation of erythropoietin in the regenerating liver that has been identified as ALR [augmenter of liver regeneration] and HSS [hepatic stimulator substance].

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