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renal brush-border neutral proteinase

This enzyme, called also kidney brush-border neutral proteinase and being referred to as neprilysin, is a neutral endopeptidase that has been isolated rabbit kidneys (Kerr and Kenny, 1974). It is enriched in kidney brush border and kidney microvillar fractions (George and Kenny, 1973; Booth and Kenny, 1974). The enzyme is identical with enkephalinase (EC 3.4.24.11) (Malfroy and Schwartz, 1984). In the nomenclature of CD antigens the enzyme has been given the designation CD10.

For additional information on CD antigens see also: CD antigens Dictionary.

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