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remote cell death

this term has been used to refer to cell death of neurons observed in regions distant from, but functionally connected to, the primary site of a lesion after focal brain damage (Block et al, 2005). These remote effects may be neuroprotective and have been shown to be associated with inflammation (Viscomi et al, 2008) and inflammation-modulating drugs in particular (for overview see: Viscomi et al, 2009). Viscomi et al (2010) have reported that the endocannabinoid system is a key participant in the determination of cell fate in remote cell death and its associated mechanisms.

For other entries pertaining to cell death mechanisms see also the Apoptosis and Cell Death Dictionary section of this encyclopedia.

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