relaxin-like peptide family
The relaxin-like peptide family belongs to the insulin superfamily and consists of various secreted peptide hormones with high structural similarity (two-chain structure and three disulfide bonds in a disposition identical to that of insulin) but low sequence similarity (Wilkinson et al, 2005; Tregear et al, 2009). Members of this family are
relaxin 1,
relaxin 2
relaxin 3,
and the insulin-like peptides
INSL3, (RLF [relaxin-like factor])
INSL4 (EPIL [early placenta insulin-like peptide] or placentin),
INSL5
INSL6.
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