receptor dog cDNA 1 |
Receptor Expressed in Lymphoid Tissues |
decapentaplegic-Vg-related-6 |
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A term describing the loss of surface receptors for growth factors and cytokines observed frequently after binding of a growth factor to its receptor. Receptor downregulation is the result of ligand induced internalization of receptor/ligand complexes and their subsequent degradation by lysosomes. In addition, internalized receptor molecules can be recycled also. See also: receptor transmodulation.
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