preapoptotic cell stress response |
pre B-cell colony enhancing factor |
SPLUNC-3 |
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[pre-basophil and mast cell progenitor]
abbr. pre-BMPs. This cell type is found in a population of granulocyte-macrophage progenitors that were highly enriched in the capacity to differentiate into basophils and mast cells while retaining a limited capacity to differentiate into myeloid cells. STAT5 signaling has been shown to be required for the differentiation of these progenitor cells into both basophils and mast cells. C/EBP-alpha has been identified as the critical basophil transcription factor for specifying basophil cell fate and MITF as the crucial transcription factor
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