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pre-basophil and mast cell progenitors

[pre-basophil and mast cell progenitor]

abbr. pre-BMPs. This cell type is found in a population of granulocyte-macrophage progenitors that were highly enriched in the capacity to differentiate into basophils and mast cells while retaining a limited capacity to differentiate into myeloid cells. STAT5 signaling has been shown to be required for the differentiation of these progenitor cells into both basophils and mast cells. C/EBP-alpha has been identified as the critical basophil transcription factor for specifying basophil cell fate and MITF as the crucial transcription factor ... ... ... ... ... Subscribe to continue reading! ... ...

 

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