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phenylalanyl-tRNA synthetase

abbr. FARS or PheRS [Phe-tRNA Synthetase]. This Aminoacyl-tRNA synthetase, which plays a critical role in translation by charging tRNAs with the cognate amino acid, is a heterodimeric protein of two alpha and two beta subunits (Rodova et al, 1999). It is being referred to also as Phenylalanine-tRNA ligase or Phenylalanine translase. In the nomenclature of enzymes the synthetase has been given the designation EC6.1.1.20.

The catalytic subunit is encoded by gene FARSA [phenylalanyl-tRNA synthetase subunit alpha], referred to also as FRSA, FARSL [ ... ... ... ... ... Subscribe to continue reading! ... ...


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