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permeability transition pore

[permeability transition pores, mitochondrial permeability transition pore, mitochondrial permeability transition pores, mitochondrial permeability transition pore complex, mitochondrial permeability transition pore complexes]

The mitochondrial permeability transition pore complex (abbr. PTPC) is formed at contact sites between the mitochondrial outer and inner membranes. The pore consists of a complex of the voltage-dependent anion channel (VDAC), the adenine nucleotide translocator (ANT), and cyclophilin-D (for recent overview see also: Siemen and Ziemer, 2013; Brenner and Moulin, 2012; Bernardi and von Stockum, 2012; Rasola et al, 2010).

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