oval cells

[oval cell]

These cells are found in the liver after extensive tissue injury and appear to constitute a kind of facultative hepatic stem cell or commited progenitor cell type that can differentiate into hepatocytes and cholangiocytes (Lowes et al, 2003). These cells therefore are bipotential transit-amplifying cells (Alison et al, 2004). See also: hepatoblasts, facultative stem cells.

Oval cells, which accumulate in response to various disease states and toxin-induced injuries within the liver parenchyma (Farber, 1956; Popper et al, 1957), are also being referred to as atypical ductal cells. These cells are being referred to also as ... ... ... ... ... Subscribe to continue reading! ... ...