non-apoptotic cell death

this collective term - a definition by exclusion - refers to cell death modalities that do not show morphological changes such as chromatin condensation and nuclear fragmentation or biochemical changes such as the activation of caspases, both of which are considered characteristics of cell death by apoptosis. As such, non-apoptotic cell death can be classified also as Non-canonical cell death. Non-apoptotic cell death modalities may be activated independently of apoptosis or are activated under conditions where the apoptosis process fails to execute, which depends on cell type and/or trigger mechanisms.

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Entry last modified: February 2024