neuropeptide SS
abbr. NPSS. This bioactive neuropeptide (SAWGSWS; Ser-Ala-Trp-Gly-Ser-Trp-Ser) has been identified as a cryptide by Kotlinska et al (2012) who reported that the sequence is contained within the sequence of the murine neuropeptide FF precursor. Neuropeptide SS has been shown to inhibit morphine antinociception and the effect is reversed by RF9, an antagonist of neuropeptide FF receptors.
See also: hormones/neuropeptide MiniCOPE dictionary for hormonally active proteins, peptides, neuropeptides, regulatory peptide factors, prohormones and their receptors.
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Entry last modified: January 2014
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