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neuropeptide SA

abbr. NPSA. This bioactive peptide (SAWGSWSKEQLNPQA) has been identified as a cryptide by Kotlinska et al (2012) who reported that the sequence is contained within the sequence of the murine neuropeptide FF precursor. The peptide resides between positions 85 and 99 of pro-NPFF. Neuropeptide SA has been shown to inhibit morphine antinociception and the effect is reversed by RF9, an antagonist of neuropeptide FF receptors.

See also: hormones/neuropeptide MiniCOPE dictionary for hormonally active proteins, peptides, neuropeptides, regulatory peptides, prohormones and their receptors.

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