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neuropeptide B

abbr. NPB. This neuropeptide (WYKPAAGHSSYSVGRAAGLLSGL) is closely related to neuropeptide W (Fujii et al, 2002). It contains a brominated N-terminal Trp (hence the designation "B"). Neuropeptide B is expressed in several discrete areas of the hypothalamus and midbrain (Dun et al, 2005; Schulz et al, 2007). The neuropeptide B precursor is expressed mostly at low levels in the brain, but moderate expression is seen in anterior olfactory nucleus, piriform cortex, median preoptic nucleus, basolateral amygdala, hippocampus, medial tuberal nucleus, substantia nigra, dorsal raphe nucleus, Edinger-Westphal nucleus, and the locus coeruleus (Jackson et al, 2006).

Tanaka et al (2003) have reported that intracerebroventricular injection of neuropeptide B in mice ... ... ... ... ... Subscribe to continue reading! ... ...


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