miRISC |
miR-K12-7 |
Mas-related G-protein-coupled receptor member D |
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this is one of 17 miRNAs encoded by KSHV. It can programme macrophage cytokine responses in favor of KSHV-related tumor progression. By interfering with a transcriptional regulator, this miRNA leads to the specifi induction of IL6 and IL10 by macrophages and monocytes (Qin et al, 2010).
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