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late activator antigen-presenting cells

[late activator antigen-presenting cell]

abbr. LAPCs [late activator APCs] This cell type, characterized as a population of CD45(+) mononuclear cells distinct from conventional dendritic cells, is found in virus-infected murine lungs. These cells migrate from the lungs to the draining lymph nodes late in the infection cycle (between 6 and 12 d postinfection) (Yoo et al, 2010). Upon migration to the draining lymph nodes, these cells support Th2 type CD4(+) T-cell differentiation and enhance antiviral antibody responses. Yoo et al (2012) have shown that late activator antigen-presenting cells act as key ... ... ... ... ... Subscribe to continue reading! ... ...

 

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