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large luteal cells

[large luteal cell]

abbr. LLC. These cells are cells in the corpus luteum that produce progesterone. These cells appear to be barely responsive to luteinizing hormone but are highly receptive to prostaglandin F2-alpha (Hansel and Dowd, 1986; Pitzel et al, 1990) and also produce oxytocin (Rodgers et al, 1983; Theodosis et al, 1986). These cells are derived from granulosa cells and are being referred to also as granulosa-lutein cells in primates (Hansel and Dowd, 1986; Pitzel et al, 1990; Niswender et al, 2000). See also: small luteal cells.

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