kielin/chordin-like protein

abbr. KCP (the approved gene symbol, but a term with multiple meanings). Also: kielin-like protein. An alternative designation is CRIM2 [cysteine-rich BMP regulator-2].

Kielin/chordin-like protein is a secreted protein (1,254 amino acids) that contains 18 cysteine-rich domains. It is expressed at early and late stages in the developing kidney (Lin et al, 2005). Kielin/chordin-like protein shows similarities to mouse Chordin and is most homologous to the Xenopus kielin, a secreted protein that mediates inductive activities of the embryonic midline (Matsui et al, 2000).

Kielin/chordin-like protein is a positive regulator of ... ... ... ...
 
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Entry last modified: June 2020