intervertebral disc cells

abbr. IVD cells. These cells produce the extracellular matrix components of the invertebrate disc (Sive et al, 2002; Sztrolovics et al, 2002; Chen et al, 2004), and growth factors such as bone morphogenetic proteins (Yoon et al, 2004). The nucleus pulposus in the middle of the disc is a hydrated tissue rich in aggrecan that permits the intervertebral disc to resist compressive loads and to distribute hydraulic pressure in all directions within each disc (Setton and Chen, 2004).

Depending upon their location, mature human intervertebral disc cells appear as elongated and bipolar cells (fibrocytes or fibroblasts) (outer anulus fibrosus), or as oval/spherical cells ( ... ... ... ...
 
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Entry last modified: January 2008