insulysin |
INT1L1 |
PMLs |
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This gene has been renamed Wnt-1 (see also: Wnt family). int-1 is the designation for a chromosomal integration site of MMTV [mouse mammary tumor virus] on mouse chromosome 15.
Int-1 encodes a secreted protein associated with the extracellular matrix (Bradley and Brown, 1990; Papkoff and Schryver, 1990). The human counterpart has been cloned by van't Veer et al (1984).
The gene activated on mouse chromosome 15 in the area of int-1 is a developmentally-regulated glycoprotein with significant amino acid similarity to a developmental protein of Drosophila melanogaster termed wingless (abbr. Wg
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