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immune checkpoints

[immune checkpoint]

this collective term pertains to regulatory molecules that maintain immune homeostasis under physiological conditions by providing co-stimulatory or co-inhibitory signals to various cell types of the immune system, including T-cells, dendritic cells, and NK-cells. These checkpoint molecules act through immune checkpoint receptors and their associated signalling pathways and protect healthy cells from adaptive immune responses. They also cause cell activation and activate lymphocytes ... ... ... ... ... Subscribe to continue reading! ... ...

 

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