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[induced pluripotent stem cells] abbr. often iPSCs. These cells are pluripotent stem cells expressing many of the genetic and phenotypic characteristics of embryonic stem cells (Takahashi and Yamanaka, 2006; Takahashi et al, 2007). These cells have been obtained after retrovirus-mediated transfer into adult mouse and human fibroblastic cells of four factors (OCT4, SOX2, KLF4 and myc) known to be among those playing a central role in the maintenance of embryonic stem cell identity both in mice and humans
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