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human papillomavirus type 16 E5 protein

[HPV16 E5 protein] This protein (83 amino acids) is encoded in the genome of high-risk human papillomavirus type 16 (HPV16), the primary causative agent of cervical cancer. E5 protein has been shown to associate with internal membranes (endoplasmic reticulum, Golgi apparatus, perinuclear region) (Krawczyk et al, 2010). E5 protein has properties of an oncoprotein as demonstrated by its ability to induce anchorage-independent growth in murine fibroblasts and human keratinocytes (Pim et al, 1992). High-level expression of the protein in the skin of transgenic mice ... ... ... ... ... Subscribe to continue reading! ... ...

 

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