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histone H2B

Histone H2B is one of the core components of nucleosome that compact DNA into chromatin (DeLange and Smith, 1971).

Role as moonlighting protein

Apart from its role in chromatin, Histone H2B has other functions and thus can be regarded as a member of a growing group of proteins referred to as moonlighting proteins.

Histone H2B has been identified as one of four cationic proteins in the acidic extract from the epidermal mucus of the Atlantic cod (Gadus morhua). The protein shows antimicrobial activity against Bacillus megaterium, Escherichia coli and Candida albicans (Bergsson et al, 2005).

Tagai et al (2011) have reported an antimicrobial activity of calf thymus histone H4 for Escherichia coli.

Silphaduang U et al (2006) have reported that ... ... ... ... ... Subscribe to continue reading! ... ...


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