hepatitis C virus NS2 protein

[hepatitis C virus nonstructural protein 2; HCV NS2 protein; NS2 protein] This protein is a non-structural protein contained within the viral polyprotein encoded by the genome of the positive-strand RNA virus Hepatitis C virus. NS2 was initially discovered to be a zinc-dependent autoprotease that acts in concert with another viral protein, NS3 [hepatitis C virus nonstructural protein 3] for cleavage of the NS2/NS3 junction within the viral polyprotein (Lorenz et al, 2006; Kilver et al, 2006; Santolini et al, 1995; Welbourn and Pause, 2007).

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Entry last modified: March 2015