hematopoietic stem cell antigen |
hematopoietic stem cell niche |
EGF-like transforming growth factor |
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This biochemically uncharacterized factor (larger than 200 kDa) is produced by murine bone marrow stromal cells (Cherry et al, 1994). The factor is most likely not identical with G-CSF, M-CSF, GM-CSF, SCF, IL6, or IL3. It attracts blastic cells in a low-density fraction, which are CD90(low), wheat germ agglutinin (WGA) high, H-2K high, (CD5(-), CD8-alpha(-), CD4(-), CD45(-), and slg (-).
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