GAS2-related protein on chromosome 22 |
gas-5 |
CCK-2 receptor |
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[Growth arrest-specific gene-3] gas-3 is one of the growth arrest-specific genes identified in quiescent, serum-starved NIH 3T3 mouse fibroblasts (see: gas genes).
gas-3 is expressed in resting but not in proliferating 3T3 mouse fibroblasts. The rat and human homolog of gas-3 is the peripheral myelin protein-22 gene PMP22, which encodes a 22 kDa integral membrane glycoprotein of peripheral myelin (Welcher et al, 1991; Snipes et al, 1992). The protein also appears to be the same as PAS2, a glycoprotein in bovine
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