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gamma-core motif

[gamma-core signature]

a structural signature found among virtually all classes of cysteine-containing antimicrobial peptides. This motif is seen in host defense peptides from organisms spanning more than 2.6 billion years of evolution Yount and Yeahman, 2006).

Many toxins also possess the gamma-core signature, consistent with discoveries of their direct antimicrobial activity. Many microbicidal chemokines (kinocidins) contain iterations of the gamma-core motif.


For information on other protein domains and sequence motifs see also the Protein domains/sequence motifs Dictionary section of this encyclopedia.

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