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fibroblast-pneumonocyte factor

This poorly characterised activity is found in the conditioned medium of mature (Day 21) rat lung fibroblasts (pneumocytes). It stimulates growth and differentiation of fetal type II epithelial cells. The conditioned medium of fetal fibroblasts (Day 17) contains a protein factor that blocks the activity of fibroblast-pneumonocyte factor. The blocking factor is one of the molecular forms of TGF-beta.

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