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erythroid suppressor cells

[erythroid suppressor cell]

This cell type (see also: erythroid cells), referred to also as CD71(+) erythroid cells, represents a population of erythroid precursor cells coexpressing the transferrin receptor CD71 and erythroid marker TER-119 (Elahi S et al, 2013). The cells possess immunosuppressive properties and are physiologically enriched in neonatal mice and human cord blood. Neonatal erythroid suppressor cells have been shown to express the enzyme arginase-2, and arginase activity is essential for the immunosuppressive properties. Ablation of erythroid suppressor cells in neonatal mice, or the decline in number of these ... ... ... ... ... Subscribe to continue reading! ... ...

 

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