EI |
EIA |
Beta-2-M |
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[etoposide-induced 2.4 mRNA; Etoposide-induced protein 2.4 homolog]
The murine ei24 gene is an immediate-early response gene the expression of which is regulated directly by the tumor suppressor protein p53. ei24 has been shown to suppress cell growth, and its overexpression induces cell death by apoptosis (Gu et al, 2000).
The human homolog has been identified as PIG8 [p53-induced gene 8] by Polyak et al (1997). In databanks the gene is being referred to also as TP53I8 [TP53-induced 8]. Gu et al (2000) have corrected the PIG8
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