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dermis-derived epithelial progenitor-1

abbr. DEEP cells or DEEP-1 cells. These cells with properties of stem cells have been obtained from mouse embryonic skin. The cells show epithelial morphology. Cells kept confluent spontaneously form spheroids and continuously grow even in spheroids. The cells express a variety of cytokeratins, E-cadherin, and are negative for the expression of vimentin, nestin, and kit. They express epithelial stem cell markers such as p63, integrin-beta-1, and S100A6. On exposure to TGF-beta in culture, some of the ... ... ... ... ... Subscribe to continue reading! ... ...

 

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