casein-beta(193-207) |
casein-beta(197-213) |
TGF-beta induced factor-2 |
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Also: beta-casein(193-209). This fragment of bovine beta-casein with the sequence YQEPVLGPVRGPFPIIV has been identified by Coste et al (1992). It is obtained through pepsin / chymosin digestion of caseins. Coste et al (1992) have reported that the peptide is mitogenic for lymphocytes (primed lymph node cells and unprimed spleen cells) of rats.
Sandré et al (2001) have reported that the peptide possesses immunoregulatory activities. It up-regulates MHC class II antigen expression and the phagocytic activity of macrophages derived from bone marrow of germfree and from human
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