border-associated macrophages

abbr. BAMs; also: CNS-associated macrophages in some publications (abbr. CAMs) or Non-parenchymal Brain Macrophages. These collective terms refers to non-parenchymal macrophages in the central nervous system (Mrdjen et al, 2018; Kierdorf et al, 2019). Border-associated macrophages reside within the tissue interfaces that separate CNS from periphery (such as meninges, perivascular spaces, and choroid plexus). It is thought that these cells prevent infection and support barrier functions (Kierdorf et al, 2019). Note the remark on terminology in the entry CNS-resident macrophages.

Most border-associated macrophages share a core transcriptional signature ... ... ... ...
 
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Entry last modified: December 2023