ADM1 |
ADM2 |
Wnt-11 |
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adm-1 (a disintegrin and metalloprotease domain) is a Caenorhabditis elegans gene identified by Podbilewicz (1996). The encoded protein is related to PH-30 (ADAM1 and ADAM2), a protein implicated in sperm-egg fusion. adm-1 protein localizes to the plasma membrane of embryonic cells and to the sheath cells of sensory organs, suggesting a function in cell adhesion. adm-1 expression in the hypodermis, pharynx, vulva, and mature sperm is consistent with a putative role in somatic and gamete cell fusions.
In some databanks the protein is being referred to as ADAM14. The same protein has been identified independently as UNC71.
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